Myxoma is a rare, benign stromal tumor of mesenchymal origin often confused with other conjunctival stromal tumors. This study evaluated the literature concerning the surgical management of odontogenic myxoma, and reports the longterm outcome of a case managed. Reconstructive considerations by means of the vascularized fibular free flap. An atrial myxoma is a benign tumor of the heart,commonly found within the le. Myxomas have a gelatinous consistency, resembling the fetal umbilical cord. Odontogenic myxoma is an uncommon benign mesenchymal odontogenic tumor arising from the dental papilla, follicle, or the periodontal ligament.
Sometimes, malignant tumors can undergo myxoid degeneration, making difficult to distinguish from myxomas on an mri. Conjunctival myxomas are thought to originate in tenons capsule and can masquerade as conjunctival lymphoma, lymphangioma, ocular surface squamous neoplasia ossn, or amelanotic melanoma. Majority of myxomas that occur are present on the left side of the heart. But the present case was a five years old male pomeranian. Report of two cases sridhar p reddy 1, ananth naag 1, bina kashyap 2 1 department of oral and maxillofacial surgery, st joseph dental college and hospital, duggirala, eluru, andhra pradesh, india 2 department of oral pathology, st joseph dental college and hospital, duggirala, eluru, andhra pradesh, india. Focal mucinous degeneration of skin soft tissue may be due to cysts, ganglion, mucinosis, myxedema, nodular fasciitis. Odontogenic myxomas are benign but locally aggressive neoplasms found almost exclusively in the jaws and arise only occasionally in other bones. It is nonencapsulated, arises from odontogenic ectomesenchyme, develops solely in the jaws, and represent a small percentage of odontogenic tumor overall. The odontogenic myxoma is an uncommon benign odontogenic tumor arising from embryonic connective tissue associated with tooth formation. It consists of scarce cells with a spindle or star shape embedded in a. According to the world health organization who, the odontogenic myxoma is classified as an odontogenic tumor of ectomesenchymal origin. As it swings, the myxoma may move in and out of the nearby mitral valve, which opens from the left atrium into the left ventricle.
Because the tumors are intravascular and friable, myxomas account for most cases of tumor embolism, which occurs in about 3040% of patients. Myxoma as stated is a tumor present near the heart. Rare appearance of an odontogenic myxoma in conebeam computed tomography. Director of the postgraduate degree in oral and maxillofacial surgery and traumatology. Clinicoradiographic examination of odontogenic myxoma. Pdf odontogenic myxoma is a benign odontogenic tumor with locally. Odontogenic myxoma genetic and rare diseases information. Odontogenic myxoma is a slowgrowing, painless, and siteaggressive tumor. Odontogenic myxoma of the maxilla a rare case report.
Despite being benign, it has a high recurrence rate and is troublesome to manage surgically. Surgical management of an uncommon cutaneous myxoma. Benign odontogenic myxoid lesion composed of spindled to stellate cells. A large myxoma occupying in the left atrium producing mitral stenosis and regurgitation was demonstrated by 2d echocardiographic images in this case. Primary intracardiac tumors are rare and approximately 50% are myxomas. A primary tumor of the heart a r shoukat1, sachin patil2 1associate professor, department of medicine, m. A myxoma is a benign tumor in the heart most commonly found in the left atrium. Atrial myxoma free download as powerpoint presentation. Case report perou, maurice l kolis, julius a zaeske, edward v borja, salvador r. Pronunciation of myxoma with 1 audio pronunciation, 7 synonyms, 1 meaning, 9 translations, 1 sentence and more for myxoma. Odontogenic myxoma om is a benign intraosseous neoplasia, not very frequent, 1 but with high infiltrative potential that makes it a locally invasive tumor.
Atrial myxomas are the most common primary cardiac tumors. Myxomas are the most common primary cardiac tumor in adults, and are most commonly found within the left atrium. Despite the benign nature of this lesion, there is a high. Other tumors with myxoid features subtypes include. Pdf rare appearance of an odontogenic myxoma in cone.
Odontogenic myxoma is a benign odontogenic tumor with locally aggressive behavior, and is relatively rare in the oral cavity. Odontogenic myxoma of the jaws is a rare slow growing, benign tumor of mesenchymal tissue origin and is characterized grossly by mucoid or gelatinous graywhitish tissue that replaces the cancellous bone and expands the cortex. Medical college, gulbarga, karnataka, india, 2postgraduate student, department of internal medicine, m. There are currently no clear surgical management guidelines for odontogenic myxoma, and a variety of approaches may be used. Third most frequent odontogenic tumor after odontoma and ameloblastoma recurrence rate 25% odontogenic myxoma. A myxoma in the left atrium often grows from a stalk and swings freely with the flow of blood. Surgical management of an uncommon cutaneous myxoma in a dog.
They may be derived from modified fibroblast cells. It can occur at any age but most commonly in the second and third decades of life. Sucessful threedimensional reconstruction using transesophageal echocardiography in a. Odontogenic myxoma ddmfr oral and maxillofacial radiology. Odontogenic myxoma of maxilla in an atypical location. Pdf rare appearance of an odontogenic myxoma in conebeam. The tumour arose in a 53yearold patient, recurred two times after extended maxillectomy and ultimately caused the patients death by uncontrollable local disease with infiltration of the cranial cavity. The evidence for its odontogenic origin arises from its almost exclusive location in the toothbearing areas of the jaws, its occasional association with missing or unerupted teeth and the presence of. Operation for resection of a cardiac myxoma is indicated whenever a myxoma is diagnosed. An irregular soft tissue mass lesion is seen arising from right maxillary bone alveolar process, measuring 6 x 4. Treatment is necessary to avoid metastasis and the formation of clots. Management of odontogenic fibromyxoma in pediatric nigerian patients. The odontogenic myxoma is generally considered to be a rare neoplasm unique to the jaws. It presents local invasiveness and tendency to recurrence.
There is great controversy about the origin of myxo matous tumors. Treatment of recurrent mandibular myxoma by curettage and. Odontogenic myxoma is a rare and locally invasive benign neoplasm found exclusively in jaws. Medical college, gulbarga, karnataka, india fail to identify the underlying abnormality. Jun 20, 2019 symptoms from a cardiac myxoma are produced by mechanical interference with cardiac function or embolization and more pronounced when the myxomas are leftsided, racemose, and over 5 cm in diameter. We report two cases of myxoma, which were misdiagnosed initially and latter. These tumors are usually located on the atrial septum. An unusual presentation of this tumor as a rapidly expanding lesion in the right maxilla of an infant is.
Odontogenic myxoma of the maxilla a rare case report ramkumar subramaiam, 1 sangeetha narashiman, 2 malathi narasimhan, 3 veda giri, 4 and santhosh kumar 5 1 professor, department of oral and maxillofacial surgery, faculty of dental sciences, sri ramachandra university, ramachandra nagar, porur chennai, tamilnadu, india. As a myxoma, this tumor consists mainly of spindle shaped cells and scattered collagen fibers distributed through a loose, mucoid material. We report a case of a large myxoma in the right atrium, which is an uncommon location for this type of tumor. In the international histological classification of odontogenic tumors, odontogenic myxoma om is defined as a benign odontogenic tumor of mesenchymal origin that is locally invasive and consists of rounded and angular cells lying in. Activating gsalpha mutation in intramuscular myxomas with and without fibrous dysplasia of bone. Epidemiology typically seen in the 2nd to 3rd decades of life slightly earlier than ameloblastomas. A case of large left atrial myxoma presenting as atrial. Case report open access surgical management of odontogenic.
Myxomas occur more frequently on the limbs, the back or the groin 10. This tumor is extremely uncommon in children and exceptionally rare in infants. Myxoma is a rare benign soft tissue tumor composed of fibroblasts embedded in abundant myxoid stroma. There are two broad geographic types of myxoma virus, californian and south american. Odontogenic myxoma is a rare tumour of the jaw, making both its diagnosis and management challenging. Seventy five percent of all myxomas are found in the left atrium, and almost all other myxomas are found in the right atrium. Odontogenic myxomas are rare tumors that involve the mandible or maxilla and account for 36% of odontogenic tumors typically seen in the 2 nd to 3 rd decades of life slightly earlier than ameloblastomas. Intramuscular myxoma is a rare benign soft tissue tumor. Odontogenic myxoma is a rare slow growing, benign, locally aggressive tumor of ectomesenchymal origin with or without odontogenic epithelium, comprising 3%. A large myxoma occupying in the left atrium producing mitral stenosis and regurgitation was demonstrated by. It is very rare for a myxoma to be found in either of the ventricles. This study evaluated the literature concerning the surgical management of odontogenic myxoma, and reports the longterm outcome of a. Odontogenic myxoma are rare, benign intraosseous lesions, arising from embryonic connective tissue, associated to odontogenesis of dental bud.
Multidisciplinary planning is required for the rehabilitation of these cases. Californian myxoma virus is found on the west coast of the usa, the baja peninsula of mexico, and the southwest coast of canada. Large asymptomatic left atrial myxoma with ossification. The tumor is derived from multipotent mesenchymal cells. Odontogenic myxoma is an uncommon benign tumor that mainly affects the mandible, with a peak incidence in the second to fourth decades of life and predilection for the female sex. If you have problems viewing pdf files, download the latest version of adobe reader for language access assistance, contact the ncats public information officer genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree. They are usually small or moderate in size by the time of the diagnosis, exhibiting non specific cardiac or systemic symptoms, and are most frequently soft and friable without microscopic signs of ossification. Pdf odontogenic tumors represents a broad spectrum of lesions ranging from benign. The odontogenic myxoma is a rare neoplasia of the jaws, benign but locally aggressive and has a high recurrence rate. Educational video created by unmc college of dentistry class of 2016 dental students. It occurs in the second and third decades, predominantly affects females more than males. We describe herein an extremely rare case of an asymptomatic giant left atrial myxoma with angiographic neovascularization.
Odontogenic myxoma om is a benign intraosseous tumor, but locally invasive, having a high rate of recurrence. Pdf management of odontogenic fibromyxoma in pediatric. Conjunctival myxomas are thought to originate in tenons capsule and can masquerade as conjunctival lymphoma, lymphangioma, ocular surface. The majority of myxomas are located in the left atrium and have variable clinical presentation. The lack of specific symptoms and widely used laboratory tests makes the diagnosis quite difficult. The mandibular odontogenic myxoma is a tumor of mesenchymal origin. Odontogenic myxoma is a rare and locally invasive benign neoplasm. Pubmed is a searchable database of medical literature and lists journal articles that discuss odontogenic myxoma. Although cardiac myxoma usually presents as a benign neoplasm, reports suggesting its malignancy, including recurrence of the tumor, locally invasive myxoma, extension from the heart, and distant metastasis are increasing.
Introduction odontogenic myxoma om is classified as a locally invasive, nonmetastasizing benign tumor, which presents in 3% to 6% of all odontogenic tumors, of the jaws by world health organization who. To the best of our knowledge, there have not been any reported cases of an association of intramuscular myxoma with. Atypical size and location of a right atrial myxoma. Received 5 july 1983, accepted 4 january 1984 the odontogenic myxoma is a relatively rare benign neoplasm of bone occurring in the jaws.
It represents approximately 3 6% of all odontogenic tumors. Treatment, symptoms, causes, complications, diagnosis. Pdf odontogenic fibromyxoma ofm is a benign, locally invasive and. About 75% of myxomas are in the left atrium, usually beginning in the wall that divides the lower chambers of the heart ventricles and growing into the atrium. Left atrial myxomamartika celaya, miranda bliss, roz ramlow 2. Mar 19, 2012 the odontogenic myxoma is an uncommon benign odontogenic tumor arising from embryonic connective tissue associated with tooth formation. A case of odontogenic myxoma with unusual histological. Odontogenic myxoma is a rare, benign, locally aggressive and non metastasizing neoplasm which is believed to arise from the odontogenic ectomesenchyme and bears a close microscopic resemblance to mesenchymal portion of a tooth germ. Case report open access surgical management of odontogenic myxoma. Myxoma is mostly seen in adult or elderly animals and although there is no sex predilection, it is supposed that doberman pincher and german shepherd dogs have a racial predisposition 8. Odontogenic myxoma is a rare, benign intraosseous tumor. Clinical case presentation luis ernesto escamilla cidel, rafael ruiz rodriguez, adalberto mosqueda taylorii cirujano maxilofacial radicado en pachuca hidalgo. Generally it is a slow growing, benign mass, that occurs in the mandible. Differential diagnoses for myxoid lesions of the jaws also are discussed.
Clinical, radiological, and histopathological features should be considered when making a diagnosis. Odontogenic myxoma is an uncommon tumor of the jaws, benign but locally invasive. An odontogenic myxoma of the maxilla with an aggressive clinical course is presented. In the majority of cases, diagnosis is largely dependent on the histopathological findings. This swinging motion may plug and unplug the valve over and over again, so that blood flow stops and starts intermittently. These two classifications are 15 compared in table 2. Odontogenic myxoma om is a rare tumor that mainly affects adolescents and adults. The tumor is of mesenchymal origin, and the characteristics of the lesion have been described by various authors in 7l previous reports2. Odontogenic myxoma is a rare, locally aggressive, benign tumor of the jaws representing less than 0. We present a case of an intramuscular myxoma associated with an increased carbohydrate antigen 19.
The most aggressive diseases that affect the oral environment are considered tumors of the jaw. Ijavst an open access journal issn 23203595 international journal of advanced veterinary science and technology 75 3 derakhshanfar, a. Autogenous grafting techniques or vascularized flaps allow ridge reconstruction for implant. These genetic and molecular approaches to cardiac myxoma may prompt the develop. Tumor surgery tumor education soft tissue tumors soft. Click on the link to view a sample search on this topic. The surgical treatment is preferably done by surgical resection of the lesion, resulting in a great loss of tissue and esthetics.
Jan 30, 2019 myxoma as stated is a tumor present near the heart. Benign odontogenic neoplasm characterized by bland, spindled to stellate cells set in myxoid stroma. A case report article pdf available in journal of dental research, dental clinics, dental prospects 101. As a myxoma, this tumor consists mainly of spindle shaped cells and. It preferably locates in posterior mandibular regions, followed by the incisors, maxillary and. Odontogenic myxoma is a rare benign but locally aggressive odontogenic tumor.
Myxomas may also develop in the other heart chambers. This report describes a case of odontogenic myxoma producing diffusely dispersed calcified products in a pattern reminiscent of a fibroosseous lesion of the jaw. The radiographic appearance is very similar to that of an ameloblastoma. Odontogenic myxoma of the mandible ramya sree s1, vardendra g kulkarni2, chandrashekhar hr3, shivamurthy kc4 abstract. Odontogenic myxoma can be found most often in young adults aged 2535 years although lesions may occur over a lifetime, reporting the lowest. Clinicoradiographic examination of odontogenic myxoma with.
Peripheral odontogenic myxoma pom is extraosseous variant of odontogenic myxomas, occurring solely in the soft tissue covering the tooth bearing portion of jaws. This paper highlights how an odontogenic myxoma can produce a large. Odontogenic myxomas are rare tumors that involve the mandible or maxilla and account for 36% of odontogenic tumors 2. Pdf introduction myxomas are a group of benign rare tumors of. Odontogenic myxoma om is a benign but locally aggressive and nonmetastasising neoplasm of the jaws. Myxoma virus is a poxvirus in the genus leporipoxvirus.